GeneTex
United States (US)

Antithrombin III antibody

Cat No. GTX30705

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA 1:25,000
Not tested in other applications.

Calculated MW

53 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.2

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

human antithrombin III

Purification

fractionated antiserum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Serpin Family C Member 1,At3,At3D,Atiii,Atiii-R2,Thph7,Serpinc1

Background

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq]

Database

Research Area

Package List Price ($)
$ 319