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Antithrombin III antibody

Anti-Antithrombin III antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55514
Anti-Antithrombin III antibody used in Western Blot (WB). GTX55514

Cat. No. GTX55514

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Antithrombin III products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 33-185 of human SERPINC1 (NP_000479.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

serpin family C member 1 , AT3 , AT3D , ATIII , ATIII-R2 , ATIII-T1 , ATIII-T2 , THPH7

Background

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009]

Database

  • Gene ID: 462 SERPINC1
  • UniProt: P01008 SERPINC1

Research Area

DATA IMAGES

Anti-Antithrombin III antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55514

GTX55514 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX55514 Antithrombin III antibody.
Blue : DAPI

Anti-Antithrombin III antibody used in Western Blot (WB). GTX55514

GTX55514 WB Image

WB analysis of various sample lysates using GTX55514 Antithrombin III antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399