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Apc10 antibody

Anti-Apc10 antibody used in IHC (Paraffin sections) (IHC-P). GTX17067
Anti-Apc10 antibody used in Western Blot (WB). GTX17067
Anti-Apc10 antibody used in IHC (Paraffin sections) (IHC-P). GTX17067

Cat. No. GTX17067

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Apc10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

Positive Control

Mouse Heart Tissue Lysate(GTX27932)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APC10 antibody was raised against a 16 amino acid synthetic peptide near the center of human APC10.The immunogen is located within amino acids 60 - 110 of APC10.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

anaphase promoting complex subunit 10 , APC10 , DOC1

Background

Apc10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-Apc10 antibody used in IHC (Paraffin sections) (IHC-P). GTX17067

GTX17067 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX17067 Apc10 antibody.
Working concentration : 20 μg/ml

Anti-Apc10 antibody used in Western Blot (WB). GTX17067

GTX17067 WB Image

WB analysis of mouse heart tissue lysate using GTX17067 Apc10 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-Apc10 antibody used in IHC (Paraffin sections) (IHC-P). GTX17067

GTX17067 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX17067 Apc10 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399