GeneTex
United States (US)

Apc6 antibody [C1C3]

GTX102905_WB_19011506_573.jpg

Cat No. GTX102905

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Positive Control

A431 , H1299 , HeLaS3 , HepG2

Predict Reactivity

Mouse, Rat, Bovine, Chicken, Pig, Xenopus laevis, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Apc6. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ANAPC6 antibody, APC6 antibody, CUT9 antibody, CDC16 antibody, cyclosome subunit 6 antibody, anaphase-promoting complex subunit 6 antibody, "anaphase-promoting complex, subunit 6 antibody", cell division cycle protein 16 homolog antibody, CDC16Hs antibody, cell division cycle 16 homolog (S. cerevisiae) antibody

Cellular Localization

Centrosome

Background

This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
Show More +

Database

Research Area

DATA IMAGES
GTX102905_WB_19011506_573.jpg

GTX102905 WB Image

Sample(30 μg of whole cell lysate)
A:A431(GTX27909)
B:H1299
C:HeLa S3(GTX14654)
7.5% SDS PAGE
GTX102905 diluted at 1:500

SDS
Glycerol.pdf
Thimerosal.pdf