APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 10 - 20 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rabbit, Gibbon, Gorilla, Horse, Marmoset, Orangutan, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 14 amino acid peptide from 2nd extracellular domain of human Apelin Receptor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
apelin receptor , AGTRL1 , APJ , APJR , APLNR , HG11 , Apelin Receptor , APJ Receptor
Cellular Localization
Cell membrane
Background
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]
Database
Research Area
DATA IMAGES
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GTX12876 IHC-P Image
IHC-P analysis of human brain, cortex tissue using GTX12876 Apelin Receptor antibody.
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GTX12876 IHC-P Image
IHC-P analysis of human colon, carcinoma tissue using GTX12876 Apelin Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12876 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX12876 Apelin Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12876 IHC-P Image
IHC-P analysis of human brain, vessel tissue using GTX12876 Apelin Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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