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Apelin antibody

Anti-Apelin antibody used in IHC (Paraffin sections) (IHC-P). GTX37465
Anti-Apelin antibody used in IHC (Paraffin sections) (IHC-P). GTX37465
Anti-Apelin antibody used in Immunohistochemistry (IHC). GTX37465
Anti-Apelin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX37465

Cat. No. GTX37465

Reference 5

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Apelin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 1:400-800
IHC Assay dependent
Not tested in other applications.

Calculated MW

9 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 75-67 amino acids of human Apelin

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11179290

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

apelin , APEL , XNPEP2

Cellular Localization

Secreted

Background

This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-Apelin antibody used in IHC (Paraffin sections) (IHC-P). GTX37465

GTX37465 IHC-P Image

IHC-P analysis of rat ovary tissue using GTX37465 Apelin antibody.
Dilution : 1:100

Anti-Apelin antibody used in IHC (Paraffin sections) (IHC-P). GTX37465

GTX37465 IHC-P Image

IHC-P analysis of rat ovary tissue using GTX37465 Apelin antibody.

Anti-Apelin antibody used in Immunohistochemistry (IHC). GTX37465

GTX37465 IHC Image

The data was published in the journal Sci Rep in 2019. PMID: 31836787

Anti-Apelin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX37465

GTX37465 ICC/IF Image

The data was published in the journal Sci Rep in 2019. PMID: 31836787

REFERENCE

Application Reference

Wang K et al. Life Sci 2020; 242 : 117208 Cardioprotective effect of electroacupuncture in cardiopulmonary bypass through apelin/APJ signaling.
Reactivity : Rat
Georgiadou D et al. Sci Rep 2019; 9 (1) : 19077 Peptide hormone ELABELA enhances extravillous trophoblast differentiation, but placenta is not the major source of circulating ELABELA in pregnancy.
Application : IHC-P
Reactivity : Human
Weitao Ji et al. Oxidative Medicine and Cellular Longevity 2019; 2019 : Article ID 6140360 Mechanism of KLF4 Protection against Acute Liver Injury via Inhibition of Apelin Signaling.
Reactivity : Mouse
Wang Y et al. Mol Cell Biochem 2019; (Epub) Apelin promotes hepatic fibrosis through ERK signaling in LX-2 cells.
Application : IHC-P
Reactivity : Human, Mouse
Shi H et al. Biosci Rep 2017; (Epub) The mechanism of all-trans retinoic acid in the regulation of apelin expression in vascular endothelial cells.
Reactivity : Rat
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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399