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Apolipoprotein E antibody

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206
Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206
Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206
Anti-Apolipoprotein E antibody used in Western Blot (WB). GTX17206

Cat. No. GTX17206

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Apolipoprotein E products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

36 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918) , Human Liver Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E.The immunogen is located within amino acids 220 - 270 of APO-E.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

apolipoprotein E , AD2 , APO-E , ApoE4 , LDLCQ5 , LPG

Cellular Localization

Secreted

Background

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206

GTX17206 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX17206 Apolipoprotein E antibody.
Working concentration : 5 μg/ml

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206

GTX17206 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX17206 Apolipoprotein E antibody.
Working concentration : 20 μg/ml

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206

GTX17206 IHC-P Image

IHC-P analysis of human liver tissue using GTX17206 Apolipoprotein E antibody.
Working concentration : 2.5 μg/ml

Anti-Apolipoprotein E antibody used in Western Blot (WB). GTX17206

GTX17206 WB Image

WB analysis of human brain tissue lysate using GTX17206 Apolipoprotein E antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399