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Apolipoprotein E antibody

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206
Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206
Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206
Anti-Apolipoprotein E antibody used in Western Blot (WB). GTX17206

Cat No. GTX17206

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

36 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918) , Human Liver Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E.The immunogen is located within amino acids 220 - 270 of APO-E.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

apolipoprotein E , AD2 , APO-E , ApoE4 , LDLCQ5 , LPG

Cellular Localization

Secreted

Background

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206

GTX17206 IHC-P Image

IHC-P analysis of human liver tissue using GTX17206 Apolipoprotein E antibody.
Working concentration : 2.5 μg/ml

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206

GTX17206 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX17206 Apolipoprotein E antibody.
Working concentration : 5 μg/ml

Anti-Apolipoprotein E antibody used in IHC (Paraffin sections) (IHC-P). GTX17206

GTX17206 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX17206 Apolipoprotein E antibody.
Working concentration : 20 μg/ml

Anti-Apolipoprotein E antibody used in Western Blot (WB). GTX17206

GTX17206 WB Image

WB analysis of human brain tissue lysate using GTX17206 Apolipoprotein E antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399