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Arginase 1 antibody [MSVA-511R] HistoMAX™

HistoMAX
Anti-Arginase 1 antibody [MSVA-511R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04426
Anti-Arginase 1 antibody [MSVA-511R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04426
Anti-Arginase 1 antibody [MSVA-511R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04426

Cat. No. GTX04426

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-511R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all Arginase 1 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Positive Control

Liver: A strong staining should be seen in hepatocytes. Spleen: A moderate t strong positivity should be seen in granulocytes.

Negative Control

Colon: Epithelial cells, smooth muscle and the vast majority of stroma cells should stain negative (few granulocytes may stain positive).

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human ARG1 protein fragment (aa300-400)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

arginase 1

Cellular Localization

Cytoplasm , Cytoplasmic granule

Background

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-Arginase 1 antibody [MSVA-511R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04426

GTX04426 IHC-P Image

IHC-P analysis of human liver tissue section using GTX04426 Arginase 1 antibody [MSVA-511R] HistoMAX™.
Strong nuclear and cytoplasmic arginase 1 expression in all hepatocytes in a normal liver.

Anti-Arginase 1 antibody [MSVA-511R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04426

GTX04426 IHC-P Image

IHC-P analysis of human hepatocellular carcinoma tissue section using GTX04426 Arginase 1 antibody [MSVA-511R] HistoMAX™.
Hepatocellular carcinoma showing strong nuclear and cytoplasmic arginase 1 positivity in all tumor cells.

Anti-Arginase 1 antibody [MSVA-511R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04426

GTX04426 IHC-P Image

IHC-P analysis of human liver cholangiocellular carcinoma tissue section using GTX04426 Arginase 1 antibody [MSVA-511R] HistoMAX™.
Complete absence of arginase 1 immunostaining in a cholangiocellular carcinoma of the liver.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299