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Aromatase antibody

Anti-Aromatase antibody used in IHC (Paraffin sections) (IHC-P). GTX32456
Anti-Aromatase antibody used in Western Blot (WB). GTX32456
Anti-Aromatase antibody used in IHC (Paraffin sections) (IHC-P). GTX32456

Cat No. GTX32456

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP19A1 (NP_000094.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cytochrome P450 family 19 subfamily A member 1 , ARO , ARO1 , CPV1 , CYAR , CYP19 , CYPXIX , P-450AROM

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

Database

Research Area

DATA IMAGES

Anti-Aromatase antibody used in IHC (Paraffin sections) (IHC-P). GTX32456

GTX32456 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32456 Aromatase antibody.
Dilution : 1:100

Anti-Aromatase antibody used in Western Blot (WB). GTX32456

GTX32456 WB Image

WB analysis of various samples using GTX32456 Aromatase antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Aromatase antibody used in IHC (Paraffin sections) (IHC-P). GTX32456

GTX32456 IHC-P Image

IHC-P analysis of human prostate tissue using GTX32456 Aromatase antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 329