GeneTex
United States (US)

Ataxin 3 antibody

GTX30079_20180530_ICCIF_18121410_426.jpg
GTX30079_20180530_WB_18121410_638.jpg

Cat No. GTX30079

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human ATXN3 (NP_004984.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Ataxin 3,At3,Atx3,Jos,Mjd,Mjd1,Sca3,Atxn3

Background

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES
GTX30079_20180530_ICCIF_18121410_426.jpg

GTX30079 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX30079 Ataxin 3 antibody.

GTX30079_20180530_WB_18121410_638.jpg

GTX30079 WB Image

WB analysis of various samples using GTX30079 Ataxin 3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319