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Aurora A antibody

Anti-Aurora A antibody used in Western Blot (WB). GTX13408

Cat. No. GTX13408

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP

Reactivity

 Human
Package
50 μg ($399)
See all Aurora A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:5,000-1:20,000
IP 1-5μg antibody/mg lysate
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

Product Note

The epitope maps to a region between residues 75-125 of human Aurora kinase A.

Predict Reactivity

Chimpanzee, Gorilla, Orangutan, Northern white-cheeked gibbon(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide representing a portion of the protein encoded within exons 5 and 6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AIK , ARK1 , AURA , AURKA , BTAK , PPP1R47 , STK15 , STK6 , STK7 , aurora kinase A , Aurora A , ARK-1

Cellular Localization

Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Spindle pole,Cilium basal body,Centriole

Background

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Aurora A antibody used in Western Blot (WB). GTX13408

GTX13408 WB Image

WB analysis of HeLa and HepG2 whole cell lysates using GTX13408 Aurora A antibody.
Dilution : 0.2μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399