*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
AuroraA (phospho-Thr288) Antibody detects endogenous levels of Aurora A only when phosphorylated at threonine 288.
PBS (without Mg2+ and Ca2+) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
The antiserum was produced against synthesized phosphopeptide derived from human AuroraA around the phosphorylation site of threonine 288 (R -T-T(p)-L-M).
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Aurora Kinase A,Aik,Ark1,Aura,Btak,Ppp1R47,Stk15,Stk6,Stk7,Aurka
Centriole,Centrosome,Cilium basal body,Cytoplasm,Cytoskeleton,Microtubule organizing center,Spindle pole
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GTX38590 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX38590 Aurora A (phospho Thr288) antibody.