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BACE1 antibody [6J26]

Cat No. GTX52556

Host

Mouse

Clonality

Monoclonal

Clone Name

6J26

Isotype

IgG1

Application

WB, IHC

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC 1:50 - 1:100
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen corresponding to a region within amino acids 22 - 460 of human BACE-1 (Uniport: P56817)

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ASP2 , BACE , BACE1 , HSPC104 , betasecretase 1 , beta-secretase 1

Cellular Localization

Membrane,Golgi apparatus,Trans-Golgi network,Endoplasmic reticulum,Endosome,Cell surface,Cytoplasmic vesicle membrane,Membrane raft

Background

This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]

Database

Research Area

REFERENCE

There are currently no references for BACE1 antibody [6J26] (GTX52556). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for BACE1 antibody [6J26] (GTX52556). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329