Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
500 μg/ml (Please refer to the vial label for the specific concentration.)
The immunogen corresponding to a region within amino acids 22 - 460 of human BACE-1 (Uniport: P56817)
Protein G purified
From tissue culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ASP2 , BACE , BACE1 , HSPC104 , betasecretase 1 , beta-secretase 1
Membrane,Golgi apparatus,Trans-Golgi network,Endoplasmic reticulum,Endosome,Cell surface,Cytoplasmic vesicle membrane,Membrane raft
This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]