*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , Jurkat , Raji
Mouse, Bovine(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.)
Recombinant protein encompassing a sequence within the C-terminus region of human BACE2. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
AEPLC antibody, ALP56 antibody, ASP1 antibody, ASP21 antibody, BAE2 antibody, CEAP1 antibody, DRAP antibody, BACE2 antibody, Down syndrome region aspartic protease antibody, beta-site amyloid precursor protein cleaving enzyme 2 antibody, beta secretase 2 antibody, memapsin-1 antibody, beta-site APP cleaving enzyme 2 antibody, 56 kDa aspartic-like protease antibody, theta-secretase antibody, aspartic-like protease 56 kDa antibody, down region aspartic protease antibody, aspartyl protease 1 antibody, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2 antibody, asp 1 antibody, membrane-associated aspartic protease 1 antibody, beta-secretase 2 antibody, transmembrane aspartic proteinase Asp1 antibody, beta-site APP-cleaving enzyme 2 antibody
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]