GeneTex
United States (US)

BAFF Receptor antibody

GTX31252_129_IHC-P_18121410_287.jpg
GTX31252_130_WB_18121410_193.jpg

Cat No. GTX31252

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 2-5μg/ml
IHC-P Assay dependent

Note :

WB
This antibody detects a band approximately 20 kDa in Western blots of human, mouse and rat spleen lysates.

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Not tested in other applications.

Calculated MW

19 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to a region within the C-terminus of human BAFF Receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Receptor Superfamily Member 13C,Baff-R,Baffr,Bromix,Cd268,Cvid4,Prolixin,Tnfrsf13C

Background

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31252_129_IHC-P_18121410_287.jpg

GTX31252 IHC-P Image

IHC analysis of human tonsil tissue using GTX31252 BAFF Receptor antibody.

GTX31252_130_WB_18121410_193.jpg

GTX31252 WB Image

WB analysis of human (H), mouse (M) and rat (R) spleen tissue lysates using GTX31252 BAFF Receptor antibody

Package List Price ($)
$ 319