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BAFF antibody [Buffy XI]

Anti-BAFF antibody [Buffy XI] used in Western Blot (WB). GTX16087

Cat. No. GTX16087

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Buffy XI

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
50 μg ($399)
See all BAFF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

BAFF (monoclonal Buffy-XI) antibody was raised against extracellular domain of human BAFF (aa. 137-285).

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF superfamily member 13b , BAFF , BLYS , CD257 , DTL , TALL-1 , TALL1 , THANK , TNFSF20 , TNLG7A , ZTNF4

Cellular Localization

Cell membrane; Single-pass type II membrane protein

Background

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL1 (for TNF- and ApoL- related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NFkB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNFa and TRAIL,THANK was shown to activate NF-kB and c-jun N terminal kinase (JNK) and to induce apoptosis.

Database

Research Area

DATA IMAGES

Anti-BAFF antibody [Buffy XI] used in Western Blot (WB). GTX16087

GTX16087 WB Image

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399