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BAIAP2 (isoform 1) antibody, C-term

Anti-BAIAP2 (isoform 1) antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX15697
Anti-BAIAP2 (isoform 1) antibody, C-term used in Western Blot (WB). GTX15697

Cat. No. GTX15697

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-3μg/ml
IHC-P 5μg/ml
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX15697-PEP).

Product Note

This antibody is expected to recognise only human isoform 1 according to NP_059344.1.

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-SGSGTLVSTV, from the C Terminus of the protein sequence according to NP_059344.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BAI1 associated protein 2 , BAP2 , FLAF3 , IRSP53

Cellular Localization

Cytoplasm , Cytoplasm, cytoskeleton

Background

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

Database

Research Area

DATA IMAGES

Anti-BAIAP2 (isoform 1) antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX15697

GTX15697 IHC-P Image

IHC-P analysis of human cortex using GTX15697 BAIAP2 (isoform 1) antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml

Anti-BAIAP2 (isoform 1) antibody, C-term used in Western Blot (WB). GTX15697

GTX15697 WB Image

WB analysis of human brain lysate using GTX15697 BAIAP2 (isoform 1) antibody, C-term.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399