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BAK antibody

Anti-BAK antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32463
Anti-BAK antibody used in Western Blot (WB). GTX32463
Anti-BAK antibody used in Immunoprecipitation (IP). GTX32463

Cat. No. GTX32463

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IP

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all BAK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IP 1:50 - 1:200
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide of human BAK1

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL2 antagonist/killer 1 , BAK , BAK-LIKE , BCL2L7 , CDN1

Cellular Localization

Mitochondrion outer membrane

Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-BAK antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32463

GTX32463 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX32463 BAK antibody.
Blue : DAPI
Dilution : 1:100

Anti-BAK antibody used in Western Blot (WB). GTX32463

GTX32463 WB Image

WB analysis of various sample lysates using GTX32463 BAK antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-BAK antibody used in Immunoprecipitation (IP). GTX32463

GTX32463 IP Image

IP analysis of THP-1 cell lysate using GTX32463 BAK antibody.
Antibody amount : 3μg / 300μg lysate
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399