*Optimal dilutions/concentrations should be determined by the researcher.
Human Spleen shows nucleoli staining in splenocytes.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88511-PEP).
This antibody is expected to recognize both reported isoforms (NP_004630.3; NP_542433.1). Reported variants representing identical protein: NP_542434.1, NP_001092004.1, NP_542433.1 (isoform b).
Mouse, Rat, Bovine, Dog, Pig(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Peptide with sequence C-PETNAPNHPSPAEY, from the internal region of the protein sequence according to NP_004630.3; NP_542433.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
G3 Antibody , BAG6 Antibody , D6S52E Antibody
The C-terminal fragment generated by caspase-3 is cytoplasmic.
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GTX88511 IHC-P Image
IHC-P analysis of human spleen using GTX88511 BAT3 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8µg/ml