GeneTex
United States (US)

BAT3 antibody, Internal

GTX88511_925_IHC-P_18122102_921.jpg

Cat No. GTX88511

Host Goat
Clonality Polyclonal
Isotype IgG
Application IHC-P, IHC
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 3-5μg/ml
IHC Assay dependent

Note :

Human Spleen shows nucleoli staining in splenocytes.
Not tested in other applications.

Calculated MW

119 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88511-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_004630.3; NP_542433.1). Reported variants representing identical protein: NP_542434.1, NP_001092004.1, NP_542433.1 (isoform b).

Predict Reactivity

Mouse, Rat, Bovine, Dog, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-PETNAPNHPSPAEY, from the internal region of the protein sequence according to NP_004630.3; NP_542433.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

G3 Antibody , BAG6 Antibody , D6S52E Antibody

Cellular Localization

The C-terminal fragment generated by caspase-3 is cytoplasmic.

Background

This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX88511_925_IHC-P_18122102_921.jpg

GTX88511 IHC-P Image

IHC-P analysis of human spleen using GTX88511 BAT3 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8µg/ml