PBS pH7.2, 10mM NaH₂PO₄, 10mM Na₂HPO₄, 130mM NaCl, 0.1% BSA
0.02% Sodium azide
Store the peptide at -20ºC, stable for one year.
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
B Cell Cll/Lymphoma 10 , Carmen , Ciper , Clap , Imd37 , C-E10 , Me10 , Bcl10
Bcl10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl 10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl10 cellular overexpression induces JNK, p38, and NF-kappaB activation. Deregulation of Bcl10 expression was also demonstrated to be involved in cellular oncogenesis.