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BCL2L2 antibody

Anti-BCL2L2 antibody used in IHC (Paraffin sections) (IHC-P). GTX30087
Anti-BCL2L2 antibody used in Western Blot (WB). GTX30087

Cat. No. GTX30087

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all BCL2L2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human BCL2L2 (NP_001186768.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887593

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL2 like 2 , BCL-W , BCL2-L-2 , BCLW , PPP1R51

Background

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES

Anti-BCL2L2 antibody used in IHC (Paraffin sections) (IHC-P). GTX30087

GTX30087 IHC-P Image

IHC-P analysis of human stomach tissue using GTX30087 BCL2L2 antibody.
Dilution : 1:100

Anti-BCL2L2 antibody used in Western Blot (WB). GTX30087

GTX30087 WB Image

WB analysis of A549 cell lysate using GTX30087 BCL2L2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Aprelikova O et al. Clin Epigenetics 2016; 8 : 38 The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis.
Application : WB
Reactivity : Mouse
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399