GeneTex
United States (US)

BCL2L2 antibody

GTX30087_20180530_WB_18121410_103.jpg
GTX30087_20180530_IHC-P_18121410_403.jpg

Cat No. GTX30087

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

21 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human BCL2L2 (NP_001186768.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Bcl2 Like 2,Bcl-W,Bcl2-L-2,Bclw,Ppp1R51,Bcl2L2

Background

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES
GTX30087_20180530_WB_18121410_103.jpg

GTX30087 WB Image

WB analysis of A549 cell lysate using GTX30087 BCL2L2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX30087_20180530_IHC-P_18121410_403.jpg

GTX30087 IHC-P Image

IHC-P analysis of human stomach tissue using GTX30087 BCL2L2 antibody.
Dilution : 1:100

REFERENCE
Package List Price ($)
$ 319