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BCL6 antibody [BCL6/1475]

Anti-BCL6 antibody [BCL6/1475] used in Western Blot (WB). GTX34432
Anti-BCL6 antibody [BCL6/1475] used in Protein Array (Protein Array). GTX34432

Cat No. GTX34432

Host

Mouse

Clonality

Monoclonal

Clone Name

BCL6/1475

Isotype

IgG1

Application

WB, Protein Array

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2μg/ml
Protein Array Assay dependent
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

BCL5 , BCL6 , BCL6A , Bcell CLL/lymphoma 6 , LAZ3 , ZBTB27 , ZNF51 , BCL6 transcription repressor

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Database

Research Area

DATA IMAGES

Anti-BCL6 antibody [BCL6/1475] used in Western Blot (WB). GTX34432

GTX34432 WB Image

WB analysis of (A) recombinant BCL6 protein (B) HepG2 cell lysates using GTX34432 BCL6 antibody [BCL6/1475].

Anti-BCL6 antibody [BCL6/1475] used in Protein Array (Protein Array). GTX34432

GTX34432 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using bcl-6 Mouse Monoclonal Antibody (BCL6/1475). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

There are currently no references for BCL6 antibody [BCL6/1475] (GTX34432). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339