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BCOR antibody

Anti-BCOR antibody used in IHC (Paraffin sections) (IHC-P). GTX01027
Anti-BCOR antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01027
Anti-BCOR antibody used in Western Blot (WB). GTX01027

Cat No. GTX01027

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:500
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

192 kDa. ( Note )

Predict Reactivity

Sheep, Bovine, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human BCOR, corresponding to a region within the internal amino acids.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

BCL6 corepressor,ANOP2,BCL6 corepressor,BCOR,MAA2,MCOPS2

Cellular Localization

Nucleus

Background

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-BCOR antibody used in IHC (Paraffin sections) (IHC-P). GTX01027

GTX01027 IHC-P Image

IHC-P analysis of mouse colon tissue using GTX01027 BCOR antibody.
Antigen retireval : Heat mediated antigen retrieval step in citrate buffer was performed
Dilution : 1:100

Anti-BCOR antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01027

GTX01027 ICC/IF Image

ICC/IF analysis of PFA-fixed COLO205 cells using GTX01027 BCOR antibody.
Permeabilization : 0.1% Triton X-100
Dilution : 1:200

Anti-BCOR antibody used in Western Blot (WB). GTX01027

GTX01027 WB Image

WB analysis of HeLa cell lysate using GTX01027 BCOR antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 329