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BMAL1 antibody

Anti-BMAL1 antibody used in Western Blot (WB). GTX50643
Anti-BMAL1 antibody used in Western Blot (WB). GTX50643

Cat No. GTX50643

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse, Rat
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

69 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around aa.569~573 (S-S-S-I-L) derived from human BMAL1.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

aryl hydrocarbon receptor nuclear translocator like,BMAL1,BMAL1c,JAP3,MOP3,PASD3,TIC,bHLHe5

Cellular Localization

Nucleus,Cytoplasm

Background

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Database

Research Area

DATA IMAGES
Anti-BMAL1 antibody used in Western Blot (WB). GTX50643

GTX50643 WB Image

WB analysis of extracts from mouse brain tissue using GTX50643 BMAL1 antibody.

Anti-BMAL1 antibody used in Western Blot (WB). GTX50643

GTX50643 WB Image

WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.

REFERENCE
REVIEW
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