GeneTex
United States (US)

BMP10 recombinant protein

Cat No. GTX65420

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED50 is in the range of 0.3-3 ug/ml.

Calculated MW

32 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers. Store at -20ºC.

Antigen Species

Human

Region/Sequence

The sequence corresponding to a region within amino acids 324 and 424 of human BMP-10 (Uniprot: O95393)

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

BMP10, bone morphogenetic protein10, bone morphogenetic protein 10, BMP 10

Background

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-10 is essential for the proper development of the heart, but is not expressed until after cardiac patterning or looping are completed. Recombinant human BMP-10 is a 32 kDa disulfide-linked homodimer containing two 142 amino acid polypeptide chains.

Research Area

Package List Price ($)
$ 249