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BMP2 antibody

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX14933
Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX14933
Anti-BMP2 antibody used in Western Blot (WB). GTX14933
Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX14933
Anti-BMP2 antibody used in Western Blot (WB). GTX14933

Cat. No. GTX14933

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, IP, Dot, ELISA

Reactivity

 Human, Mouse, Rat, Monkey, Baboon
Package
100 μg ($429)
See all BMP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200
ICC/IF 1:2000
IHC-P Assay dependent
IHC-Fr Assay dependent
IP 1:200-1:500
Dot Assay dependent
ELISA 1:2000
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.73 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Synthetic peptide corresponding to Mouse BMP2 amino acid region 45-60 conjugated to Keyhole Limpet Haemocyanin (KLH). Sequence:SEDVLSEFELRLLSMF

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

bone morphogenetic protein 2 , AI467020 , Bmp2a

Cellular Localization

Secreted

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. While a homozygous knockout mouse for this gene exhibits embryonic lethality, conditional knockout mice have defects in bone, cartilage and heart development. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX14933

GTX14933 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX14933 BMP2 antibody.
Dilution : 1:100

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX14933

GTX14933 IHC-P Image

IHC-P analysis of baboon liver tissue using GTX14933 BMP2 antibody.
Dilution : 1:100

Anti-BMP2 antibody used in Western Blot (WB). GTX14933

GTX14933 WB Image

WB analysis of BMP2 recombinant protein using GTX14933 BMP2 antibody.
Dilution : 1:500

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX14933

GTX14933 IHC-P Image

IHC-P analysis of mouse embryo tissue using GTX14933 BMP2 antibody.
Dilution : 1:50

Anti-BMP2 antibody used in Western Blot (WB). GTX14933

GTX14933 WB Image

WB analysis of various samples using GTX14933 BMP2 antibody.
Lane 1 : HeLa whole cell lysate
Lane 2 : THP-1 whole cell lyste
Lane 3 : HepG2 whole cell lysate
Lane 4 : Huh-7 whole cell lysate
Dilution : 1:250

REFERENCE

Application Reference

X Zeng et al. Pharmacognosy Magazine 2023; Bee Pollen Stimulated BMP2 and RANK Signaling Pathway in Osteoprogenitors and Improved Bone Mineralization in Rat Model of Femur Fracture
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Package List Price ($)
$ 429