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BMP2 antibody

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64355
Anti-BMP2 antibody used in Western Blot (WB). GTX64355
Anti-BMP2 antibody used in Western Blot (WB). GTX64355
Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64355

Cat. No. GTX64355

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all BMP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2888594

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

bone morphogenetic protein 2 , BDA2 , BMP2A , SSFSC

Cellular Localization

Secreted

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64355

GTX64355 IHC-P Image

IHC-P analysis of rat heart tissue using GTX64355 BMP2 antibody.
Antigen retrieval : 10 mM citrate buffer pH 6.0 with high pressure
Dilution : 1:50

Anti-BMP2 antibody used in Western Blot (WB). GTX64355

GTX64355 WB Image

WB analysis of various sample lysates using GTX64355 BMP2 antibody.
Dilution : 1:1000
Loading : 25μg per lane
Detection : ECL Enhanced Kit.

Anti-BMP2 antibody used in Western Blot (WB). GTX64355

GTX64355 WB Image

WB analysis of various sample lysates using GTX64355 BMP2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-BMP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64355

GTX64355 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64355 BMP2 antibody.
Antigen retrieval : 10 mM citrate buffer pH 6.0 with high pressure
Dilution : 1:50

REFERENCE

Application Reference

Tan Y et al. Pharmaceuticals (Basel) 2023; 16 (3) FOXO3-Activated circFGFBP1 Inhibits Extracellular Matrix Degradation and Nucleus Pulposus Cell Death via miR-9-5p/BMP2 Axis in Intervertebral Disc Degeneration In Vivo and In Vitro.
Application : IHC-Fr
Reactivity : Rat
Song SM et al. Mater Sci Eng C Mater Biol Appl 2020; 111 : 110783 A bi-phase core-shell structure of Mg-based bulk metallic glass for application in orthopedic fixation implants.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399