Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide: LQTLRAGDEGWLVL conjugated to KLH, corresponding to amino acids 184-197 of BMP8.
Immunogen affinity purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
The Bone morphogenetic proteins (BMPs) are members of the TGF beta superfamily of cytokines that are involved in development, differentiation, and disease. The transforming growth factor beta (TGF beta) super-family consists of a large number of growth and differentiation factors, such as TGF betas, activins, inhibins, growth and differentiation factors (GDFs), and bone morphogenetic proteins (BMPs). The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4. BMP8 Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. It also plays a role in calcium regulation and bone homeostasis.