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BMP8 antibody

Anti-BMP8 antibody used in Western Blot (WB). GTX14934
Anti-BMP8 antibody used in Western Blot (WB). GTX14934

Cat. No. GTX14934

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all BMP8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IP 1:200
ELISA 1:2000
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.57-0.68 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide taken within amino acid region 160-200 on human BMP8 protein

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

bone morphogenetic protein 8b , BMP8 , OP2

Cellular Localization

Secreted

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-BMP8 antibody used in Western Blot (WB). GTX14934

GTX14934 WB Image

WB analysis of BMP8 recombinant protein using GTX14934 BMP8 antibody.
Dilution : 1:500

Anti-BMP8 antibody used in Western Blot (WB). GTX14934

GTX14934 WB Image

WB analysis of human chondrocyte lysate using GTX14934 BMP8 antibody.
Dilution : 1:500

REFERENCE

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REVIEW

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Package List Price ($)
$ 399