GeneTex
United States (US)

BMP8 antibody

BMP8-antibody_WB_GTX14934-1_18121409_850.jpg

Cat No. GTX14934

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, Dot, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

Dot: Use at a dilution of 1/2000. ELISA: Use at a dilution of 1/2000. WB: Use at a dilution of 1/500 - 1/1000. Detects a band of approximately 45 kDa. Optimal dilutions/concentrations should be determined by the end user.
PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide: LQTLRAGDEGWLVL conjugated to KLH, corresponding to amino acids 184-197 of BMP8.

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Secreted

Background

The Bone morphogenetic proteins (BMPs) are members of the TGF beta superfamily of cytokines that are involved in development, differentiation, and disease. The transforming growth factor beta (TGF beta) super-family consists of a large number of growth and differentiation factors, such as TGF betas, activins, inhibins, growth and differentiation factors (GDFs), and bone morphogenetic proteins (BMPs). The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4. BMP8 Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. It also plays a role in calcium regulation and bone homeostasis.
DATA IMAGES
BMP8-antibody_WB_GTX14934-1_18121409_850.jpg

GTX14934 WB Image

WB of BMP8 with GTX14934. Antibody dilution 1:500 in diluObuffer. Apparent MW of BMP8 is 49kDa

Package List Price ($)
$ 329