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BMPR1A antibody [4B7B2]

Anti-BMPR1A antibody [4B7B2] used in IHC (Paraffin sections) (IHC-P). GTX60675
Anti-BMPR1A antibody [4B7B2] used in ELISA (ELISA). GTX60675
Anti-BMPR1A antibody [4B7B2] used in IHC (Paraffin sections) (IHC-P). GTX60675
Anti-BMPR1A antibody [4B7B2] used in Western Blot (WB). GTX60675
Anti-BMPR1A antibody [4B7B2] used in Flow cytometry (FACS). GTX60675

Cat. No. GTX60675

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4B7B2

Isotype

 IgG1

Application

 WB, IHC-P, FACS, ELISA

Reactivity

 Human
Package
100 μg ($409)
See all BMPR1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

bone morphogenetic protein receptor type 1A , 10q23del , ACVRLK3 , ALK3 , CD292 , SKR5

Cellular Localization

Cell membrane

Background

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-BMPR1A antibody [4B7B2] used in IHC (Paraffin sections) (IHC-P). GTX60675

GTX60675 IHC-P Image

IHC-P analysis of human kidney tissue using GTX60675 BMPR1A antibody [4B7B2].

Anti-BMPR1A antibody [4B7B2] used in ELISA (ELISA). GTX60675

GTX60675 ELISA Image

ELISA analysis of antigen using GTX60675 BMPR1A antibody [4B7B2].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-BMPR1A antibody [4B7B2] used in IHC (Paraffin sections) (IHC-P). GTX60675

GTX60675 IHC-P Image

IHC-P analysis of colon cancer tissue using GTX60675 BMPR1A antibody [4B7B2].

Anti-BMPR1A antibody [4B7B2] used in Western Blot (WB). GTX60675

GTX60675 WB Image

WB analysis of HEK293 (1) and BMPR1A (AA: 179-378)-hIgGFc transfected HEK293 (2) cell lysate using GTX60675 BMPR1A antibody [4B7B2].

Anti-BMPR1A antibody [4B7B2] used in Flow cytometry (FACS). GTX60675

GTX60675 FACS Image

FACS analysis of Jurkat cells using GTX60675 BMPR1A antibody [4B7B2].
Green : BMPR1A
Purple : negative control

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409