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BMPR1B antibody [3E12]

Anti-BMPR1B antibody [3E12] used in IHC (Paraffin sections) (IHC-P). GTX52506

Cat No. GTX52506

Host

Mouse

Clonality

Monoclonal

Clone Name

3E12

Isotype

IgG2

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:100 - 1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Specificity/Sensitivity

This antibody was selected for its ability to detect human BMPR1B. No cross reactivity was found to ALK3 (BMPR-IA)

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant hu-ALK6 extra cellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ALK6 , AMDD , BDA1D , BDA2 , BMPR1B , CDw293 , bone morphogenetic protein receptor type 1B , BMPR-IB

Cellular Localization

Cell membrane,Membrane

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Database

Research Area

DATA IMAGES

Anti-BMPR1B antibody [3E12] used in IHC (Paraffin sections) (IHC-P). GTX52506

GTX52506 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52506 BMPR1B antibody [3E12].

REFERENCE

There are currently no references for BMPR1B antibody [3E12] (GTX52506). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for BMPR1B antibody [3E12] (GTX52506). Be the first to share your experience with this product.
SDS
PBS.pdf