GeneTex
United States (US)

BMPR1B antibody

GTX32474_20180530_IHC-P_1_18121410_409.jpg
GTX32474_20180530_IHC-P_18121410_637.jpg
GTX32474_20180530_WB_18121410_105.jpg

Cat No. GTX32474

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

57 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human BMPR1B (NP_001194.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Bone Morphogenetic Protein Receptor Type 1B,Alk-6,Alk6,Amdd,Bda1D,Bda2,Cdw293,Bmpr1B

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Database

Research Area

DATA IMAGES
GTX32474_20180530_IHC-P_1_18121410_409.jpg

GTX32474 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX32474 BMPR1B antibody.
Dilution : 1:200

GTX32474_20180530_IHC-P_18121410_637.jpg

GTX32474 IHC-P Image

IHC-P analysis of mouse intestine tissue using GTX32474 BMPR1B antibody.
Dilution : 1:200

GTX32474_20180530_WB_18121410_105.jpg

GTX32474 WB Image

WB analysis of various samples using GTX32474 BMPR1B antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329