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BMPR1B antibody

Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474
Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474
Anti-BMPR1B antibody used in Western Blot (WB). GTX32474
Anti-BMPR1B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32474
Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474
Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474

Cat No. GTX32474

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
ICC/IF 1:50-1:200
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human BMPR1B (NP_001194.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

bone morphogenetic protein receptor type 1B , ALK-6 , ALK6 , AMDD , BDA1D , BDA2 , CDw293

Cellular Localization

Cell membrane,Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Database

Research Area

DATA IMAGES

Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474

GTX32474 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX32474 BMPR1B antibody.
Dilution : 1:200

Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474

GTX32474 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX32474 BMPR1B antibody.
Dilution : 1:200

Anti-BMPR1B antibody used in Western Blot (WB). GTX32474

GTX32474 WB Image

WB analysis of various sample lysates using GTX32474 BMPR1B antibody.
Loading : 25ug per lane
Dilution : 1:1000

Anti-BMPR1B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32474

GTX32474 ICC/IF Image

ICC/IF analysis of L929 cells using GTX32474 BMPR1B antibody.
Blue : DAPI
Dilution : 1:100

Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474

GTX32474 IHC-P Image

IHC-P analysis of rat ovary tissue using GTX32474 BMPR1B antibody.
Dilution : 1:200

Anti-BMPR1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32474

GTX32474 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX32474 BMPR1B antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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Package List Price ($)
$ 329