APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1/500 - 1/2000 |
1/200 - 1/1000 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human BMPR2 expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
bone morphogenetic protein receptor type 2 , BMPR-II , BMPR3 , BMR2 , BRK-3 , POVD1 , PPH1 , T-ALK
Cellular Localization
Cell membrane
Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX60414 WB Image
WB analysis of HeLa (1), A431 (2), NIH3T3 (3), Cos7 (4) and PC-12 (5) cell lysate using GTX60414 BMPR2 antibody [1F12].
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GTX60414 IHC-P Image
IHC-P analysis of kidney cancer tissue (left) and stomach cancer tissue (right) using GTX60414 BMPR2 antibody [1F12].
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GTX60414 IHC-P Image
IHC-P analysis of breast cancer tissue (left) and tonsil tissue (right) using GTX60414 BMPR2 antibody [1F12].
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GTX60414 ELISA Image
ELISA analysis of antigen using GTX60414 BMPR2 antibody [1F12].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng
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REFERENCE
There are currently no references for BMPR2 antibody [1F12] (GTX60414). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for BMPR2 antibody [1F12] (GTX60414). Be the first to share your experience with this product.