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BMPR2 antibody [3F6]

Anti-BMPR2 antibody [3F6] used in ELISA (ELISA). GTX60415
Anti-BMPR2 antibody [3F6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60415
Anti-BMPR2 antibody [3F6] used in IHC (Paraffin sections) (IHC-P). GTX60415
Anti-BMPR2 antibody [3F6] used in Western Blot (WB). GTX60415

Cat. No. GTX60415

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3F6

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μl ($409)
See all BMPR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

115 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human BMPR2 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_2887965

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

bone morphogenetic protein receptor type 2 , BMPR-II , BMPR3 , BMR2 , BRK-3 , POVD1 , PPH1 , T-ALK

Cellular Localization

Cell membrane

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-BMPR2 antibody [3F6] used in ELISA (ELISA). GTX60415

GTX60415 ELISA Image

ELISA analysis of antigen using GTX60415 BMPR2 antibody [3F6].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

Anti-BMPR2 antibody [3F6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60415

GTX60415 ICC/IF Image

ICC/IF analysis of Eca109 cells using GTX60415 BMPR2 antibody [3F6].
Green : BMPR2
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

Anti-BMPR2 antibody [3F6] used in IHC (Paraffin sections) (IHC-P). GTX60415

GTX60415 IHC-P Image

IHC-P analysis of muscle tissue (left) and kidney cancer tissue (right) using GTX60415 BMPR2 antibody [3F6].

Anti-BMPR2 antibody [3F6] used in Western Blot (WB). GTX60415

GTX60415 WB Image

WB analysis of HeLa (1), A431 (2), NIH3T3 (3), Cos7 (4) and PC-12 (5) cell lysate using GTX60415 BMPR2 antibody [3F6].

REFERENCE

Application Reference

Shintaro Mikami et al. PLoS One 2022; 17 (6) : e0270056 Nintedanib induces gene expression changes in the lung of induced-rheumatoid arthritis-associated interstitial lung disease mice.
Application : WB, IHC-P
Reactivity : Mouse
Khan S et al. Cell Death Dis 2021; 13 (1) : 11 TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy.
Application : WB
Reactivity : Mouse
Lin C et al. Biochem Biophys Res Commun 2017; (Epub) miR-3065-5p regulates mouse odontoblastic differentiation partially through bone morphogenetic protein receptor type II.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409