APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100 - 1:1000 |
1:50 - 1:200 |
Not tested in other applications.
Calculated MW
Product Note
This antibody was selected for its ability to detect human BMPR2. No cross reactivity was found to BMP R1A and R1B.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant BMP RII extra cellular domain
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
BMPR2 , BMPR3 , BMPRII , BMR2 , BRK3 , POVD1 , PPH1 , TALK , bone morphogenetic protein receptor type 2
Cellular Localization
Cell membrane
Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX52511 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52511 BMPR2 antibody [9A10].
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REFERENCE
There are currently no references for BMPR2 antibody [9A10] (GTX52511). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for BMPR2 antibody [9A10] (GTX52511). Be the first to share your experience with this product.