*Optimal dilutions/concentrations should be determined by the researcher.
|1:100 - 1:1000
|1:50 - 1:200
Not tested in other applications.
This antibody was selected for its ability to detect human BMPR2. No cross reactivity was found to BMP R1A and R1B.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
200 μg/ml (Please refer to the vial label for the specific concentration.)
Recombinant BMP RII extra cellular domain
Protein G purified
From tissue culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
BMPR2 , BMPR3 , BMPRII , BMR2 , BRK3 , POVD1 , PPH1 , TALK , bone morphogenetic protein receptor type 2
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
GTX52511 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52511 BMPR2 antibody [9A10].