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BMPR2 antibody

Anti-BMPR2 antibody used in Western Blot (WB). GTX30090
Anti-BMPR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30090
Anti-BMPR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30090

Cat. No. GTX30090

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all BMPR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

115 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 739-1038 of human BMPR2 (NP_001195.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

bone morphogenetic protein receptor type 2 , BMPR-II , BMPR3 , BMR2 , BRK-3 , POVD1 , PPH1 , T-ALK

Cellular Localization

Cell membrane

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-BMPR2 antibody used in Western Blot (WB). GTX30090

GTX30090 WB Image

WB analysis of various sample lysates using GTX30090 BMPR2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-BMPR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30090

GTX30090 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX30090 BMPR2 antibody.
Blue : DAPI
Dilution : 1:100

Anti-BMPR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30090

GTX30090 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30090 BMPR2 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399