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BMX antibody

Anti-BMX antibody used in Western Blot (WB). GTX56219
Anti-BMX antibody used in IHC (Paraffin sections) (IHC-P). GTX56219
Anti-BMX antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX56219

Cat. No. GTX56219

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all BMX products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
ICC/IF 1:100 - 1:500
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

78 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of BMX. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BMX non-receptor tyrosine kinase , ETK , PSCTK2 , PSCTK3

Cellular Localization

Cytoplasm

Background

This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-BMX antibody used in Western Blot (WB). GTX56219

GTX56219 WB Image

WB analysis of mouse brain (A) whole cell lysates using GTX56219 BMX antibody.

Anti-BMX antibody used in IHC (Paraffin sections) (IHC-P). GTX56219

GTX56219 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX56219 BMX antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-BMX antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX56219

GTX56219 ICC/IF Image

ICC/IF analysis of formalin-fixed A549 cells using GTX56219 BMX antibody.
Red : Primary antibody
Blue : DAPI
Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399