APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
| Assay dependent |
|
Note :
Sandwich ELISA
Capture : GTX40984, Detection : GTX04088, Sensitivity of this antibody pair is better than 1 pg/ml (synthetic BNP, Bachem). All pairs recognize with high sensitivity the antigen in plasma samples of patients with heart failure.
The detection antibody requires HRP conjugation. Please contact us for the conjugation service.
|
Not tested in other applications.
Calculated MW
Product Note
Human BNP and proBNP.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic human BNP peptide a.a.r. 11-22 conjugated with carrier protein.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
BNP,NPPB,natriuretic peptide B,Brain Natriuretic Peptide
Cellular Localization
Secreted
Background
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
Database
Research Area
DATA IMAGES
![Anti-BNP antibody [24C5] used in ELISA (ELISA). GTX04088](/templates/default/js/lightbox/images/loading.gif "Anti-BNP antibody [24C5] used in ELISA (ELISA). GTX04088")
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GTX04088 ELISA Image
ELISA analysis of endogenous proBNP and BNP using GTX04088 BNP antibody [24C5]. Gel filtration studies of endogenous proBNP and BNP. Proteins from one representative plasma sample of a HF patient were separated on the Superdex Peptide column (GE Healthcare). BNP immunoreactivity in fractions was measured by the 50E1-24C5 assay. The first peak corresponds to proBNP, while the second peak corresponds to the BNP form.
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REFERENCE
There are currently no references for BNP antibody [24C5] (GTX04088). Be the first to share your publications with this product.
REVIEW
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![Anti-BNP antibody [24C5] used in ELISA (ELISA). GTX04088](/upload/website/prouct_img/small/GTX04088/GTX04088_20221021__22102020_705.webp "Anti-BNP antibody [24C5] used in ELISA (ELISA). GTX04088")
![Anti-BNP antibody [24C5] used in ELISA (ELISA). GTX04088](/upload/website/prouct_img/normal/GTX04088/GTX04088_20221021__22102020_705.webp "Anti-BNP antibody [24C5] used in ELISA (ELISA). GTX04088")