GeneTex
United States (US)

BPGM antibody

GTX33041_20180530_IHC-P_18121410_495.jpg
GTX33041_20180530_WB_18121410_775.jpg

Cat No. GTX33041

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

30 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human BPGM (NP_001715.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Bisphosphoglycerate Mutase,Dpgm,Bpgm

Background

2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES
GTX33041_20180530_IHC-P_18121410_495.jpg

GTX33041 IHC-P Image

IHC-P analysis of human stomach tissue using GTX33041 BPGM antibody.
Dilution : 1:100

GTX33041_20180530_WB_18121410_775.jpg

GTX33041 WB Image

WB analysis of various samples using GTX33041 BPGM antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329