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BRG1 antibody [4E11-E11-G11]

Anti-BRG1 antibody [4E11-E11-G11] used in Immunoprecipitation (IP). GTX16472
Anti-BRG1 antibody [4E11-E11-G11] used in Western Blot (WB). GTX16472

Cat. No. GTX16472

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4E11-E11-G11

Isotype

 IgG1

Application

 WB, IP, Immunodiffusion

Reactivity

 Human
Package
100 μl ($399)
See all BRG1 products

APPLICATION

Calculated MW

185 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human BRG1 protein fragments expressed in E.coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , BAF190 , BAF190A , BRG1 , CSS4 , MRD16 , RTPS2 , SNF2 , SNF2L4 , SNF2LB , SWI2 , hSNF2b

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-BRG1 antibody [4E11-E11-G11] used in Immunoprecipitation (IP). GTX16472

GTX16472 IP Image

IP analysis was perform with HeLa lysates and either control IgG or BRG1 antibody [4E11-E11-G11]. The precipitates were detected by the same antibody.

Anti-BRG1 antibody [4E11-E11-G11] used in Western Blot (WB). GTX16472

GTX16472 WB Image

WB analysis of various cell lysates using BRG1 antibody [4E11-E11-G11] at a dilution of 1:1000.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399