APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
2 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
SK-N-SH Cell Lysate(GTX23956)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
BRG1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human BRG1.The immunogen is located within amino acids 1420 - 1470 of BRG1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , BAF190 , BAF190A , BRG1 , CSS4 , MRD16 , RTPS2 , SNF2 , SNF2L4 , SNF2LB , SWI2 , hSNF2b
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Database
Research Area
DATA IMAGES
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GTX31917 IHC-P Image
IHC-P analysis of mouse testis tissue using GTX31917 BRG1 antibody. Working concentration : 2 μg/ml
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GTX31917 WB Image
WB analysis of SK-N-SH cell lysate using GTX31917 BRG1 antibody. Working concentration : 1 μg/ml
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GTX31917 IHC-P Image
IHC-P analysis of rat brain tissue using GTX31917 BRG1 antibody. Working concentration : 5 μg/ml
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GTX31917 IHC-P Image
IHC-P analysis of rat brain tissue using GTX31917 BRG1 antibody. Working concentration : 5 μg/ml
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GTX31917 IHC-P Image
IHC-P analysis of mouse testis tissue using GTX31917 BRG1 antibody. Working concentration : 20 μg/ml
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REFERENCE
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REVIEW
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