APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:200 |
Note :
IHC-P
Heat-induced epitope retrieval (HIER) at pH 9 for 10 - 30 minutes
|
Not tested in other applications.
Calculated MW
Positive Control
Liver
PROPERTIES
Form
Liquid
Buffer
Tris, 1% BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant Human BSEP protein.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Atp Binding Cassette Subfamily B Member 11 , Abc16 , Bric2 , Bsep , Pfic-2 , Pfic2 , Pgy4 , Spgp , Abcb11
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
Research Area
DATA IMAGES
|
GTX57179 IHC-P Image
IHC-P analysis of human liver tissue using GTX57179 BSEP antibody [IHC518]
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REFERENCE
There are currently no references for BSEP antibody [IHC518] (GTX57179). Be the first to share your publications with this product.
REVIEW
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