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BTK antibody

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX02311
Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX02311
Anti-BTK antibody used in Western Blot (WB). GTX02311

Cat No. GTX02311

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
IHC-P 1:1000-1:4000
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2 μm filtered PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human Bruton Tyrosine Kinase / BTK Kinase protein

Purification

Purified by Protein A and Antigen Affinity

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Bruton tyrosine kinase , AGMX1 , AT , ATK , BPK , IGHD3 , IMD1 , PSCTK1 , XLA

Cellular Localization

Cytoplasm , Nucleus

Background

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Database

Research Area

DATA IMAGES

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX02311

GTX02311 IHC-P Image

IHC-P analysis of human spleen tissue section using GTX02311 BTK antibody.
Dilution : 1:2000

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX02311

GTX02311 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02311 BTK antibody.
Dilution : 1:2000

Anti-BTK antibody used in Western Blot (WB). GTX02311

GTX02311 WB Image

WB analysis of various samples using GTX02311 BTK antibody.
Lane A : K562 whole cell lysate
Lane B : Daudi whole cell lysate
Dilution : 1:500
Loading : 30 μg

REFERENCE

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REVIEW

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Package List Price ($)
$ 339