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BTK antibody

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX32479
Anti-BTK antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32479
Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX32479
Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX32479

Cat No. GTX32479

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTK (NP_000052.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Bruton tyrosine kinase , AGMX1 , AT , ATK , BPK , IGHD3 , IMD1 , PSCTK1 , XLA

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Database

Research Area

DATA IMAGES

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX32479

GTX32479 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX32479 BTK antibody.
Dilution : 1:100

Anti-BTK antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32479

GTX32479 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX32479 BTK antibody.
Blue : DAPI

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX32479

GTX32479 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX32479 BTK antibody.
Dilution : 1:100

Anti-BTK antibody used in IHC (Paraffin sections) (IHC-P). GTX32479

GTX32479 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32479 BTK antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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