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Bad antibody

Anti-Bad antibody used in IHC (Paraffin sections) (IHC-P). GTX31688
Anti-Bad antibody used in Western Blot (WB). GTX31688
Anti-Bad antibody used in IHC (Paraffin sections) (IHC-P). GTX31688

Cat. No. GTX31688

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Bad products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 2 μg/mL
IHC-P 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Positive Control

T24 Cell Lysate(GTX23958) , Rat Thymus Tissue Lysate(GTX24041)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad.The immunogen is located within amino acids 90 - 140 of BAD.

Purification

Purified by ion exchange chromatography

Conjugation

Unconjugated

RRID

AB_2887623

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL2 associated agonist of cell death , BBC2 , BCL2L8

Cellular Localization

Mitochondrion outer membrane,Cytoplasm

Background

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Bad antibody used in IHC (Paraffin sections) (IHC-P). GTX31688

GTX31688 IHC-P Image

IHC-P analysis of rat thymus tissue using GTX31688 Bad antibody.
Working concentration : 10 μg/ml

Anti-Bad antibody used in Western Blot (WB). GTX31688

GTX31688 WB Image

WB analysis of T24 cell lysate using GTX31688 Bad antibody.
Working concentration : (A) 0.5, (B) 1, and (C) 2 μg/ml

Anti-Bad antibody used in IHC (Paraffin sections) (IHC-P). GTX31688

GTX31688 IHC-P Image

IHC-P analysis of rat thymus tissue using GTX31688 Bad antibody.
Working concentration : 2 μg/ml

REFERENCE

Application Reference

Chen YL et al. Cancers (Basel) 2019; 11 (5) mTOR Inhibitors Can Enhance the Anti-Tumor Effects of DNA Vaccines through Modulating Dendritic Cell Function in the Tumor Microenvironment.
Application : WB
Reactivity : Mouse
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399