GeneTex

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United States (US)

Bad peptide

Cat. No. GTX27985

Application

 IP

Species

 Mouse
Package
100 μg ($179)
See all Bad products

APPLICATION

Application Note

Blocking peptide for rabbit polyconal antibody to Bad(GTX27975).

Calculated MW

18 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, BSA

Preservative

0.1% Sodium azide

Storage

Keep as concentrated solution, aliquot and store at 4ºC.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Peptide mapping to the amino terminus of mouse Bad.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL2 associated agonist of cell death , BBC2 , BCL2L8

Cellular Localization

Mitochondrion outer membrane , Cytoplasm

Background

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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Package List Price ($)
$ 179