GeneTex
United States (US)

Bag1 peptide

Cat No. GTX27986

Application Blocking
Reactivity Mouse
Species Mouse
APPLICATION

Application Note

Blocking peptide for Rabbit polyclonal to Bag-1 (GTX27976)
PROPERTIES

Form

Liquid

Buffer

PBS with 100ug BSA 0.1% sodium azide

Storage

Keep as concentrated solution, aliquot and store at 4ºC.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Bcl2-Associated Athanogene 1,Bag-1,Rap46,Bag1

Background

BAG 1 is a multifunctional protein that blocks apoptosis and interacts with several types of proteins. These include the Bcl 2 family proteins, the kinase Raf 1, certain tyrosine kinase growth factor receptors, and steroid hormone receptors, possibly by virtue of its ability to regulate the Hsp70 / Hsc70 family of molecular chaperones. BAG 1 binds the ATPase domains of Hsp70 and Hsc70, modulating their chaperone activity and functioning as a competitive antagonist of the co-chaperone Hip. Human BAG 1 (hBAG 1) cDNA is identical to a hormone receptor binding protein RAP46. Human BAG 1 protein displays different isoforms of 36 kDa, 46 kDa, and 50 kDa.

Research Area

Package List Price ($)
$ 179