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Bax antibody [1C1]

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053
Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053
Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

Cat No. GTX34053

Host

Mouse

Clonality

Monoclonal

Clone Name

1C1

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

Specificity/Sensitivity

Bax Mouse Monoclonal Antibody (1C1) detects endogenous levels of BAX

PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic Peptide of Bax

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Bcl2 Associated X, Apoptosis Regulator , Bcl2L4 , Bax

Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

GTX34053 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Kidney Tissue using Bax Mouse Monoclonal Antibody diluted at 1:200.

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

GTX34053 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcinoma Tissue using Bax Mouse Monoclonal Antibody diluted at 1:200.

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

GTX34053 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Testis Tissue using Bax Mouse Monoclonal Antibody diluted at 1:200.

REFERENCE

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REVIEW

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Package List Price ($)
$ 319