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Bax antibody [1C1]

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053
Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053
Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

Cat. No. GTX34053

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1C1

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Bax products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

synthetic peptide derived from Bax at 30-110 aa.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BAX,BCL2 associated X, apoptosis regulator,BCL2L4,Bax

Cellular Localization

Mitochondrion membrane,Cytoplasm

Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

GTX34053 IHC-P Image

IHC-P analysis of rat testis tissue using GTX34053 Bax antibody [1C1].
Dilution : 1:200

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

GTX34053 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX34053 Bax antibody [1C1].
Dilution : 1:200

Anti-Bax antibody [1C1] used in IHC (Paraffin sections) (IHC-P). GTX34053

GTX34053 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX34053 Bax antibody [1C1].
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399