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Bcl-2 antibody [bcl-2/100/D5]

Anti-Bcl-2 antibody [bcl-2/100/D5] used in IHC (Paraffin sections) (IHC-P). GTX01935

Cat. No. GTX01935

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 bcl-2/100/D5

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($409)
See all Bcl-2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Synthetic peptide sequence (GAAPAPGIFSSQPGC-COOH).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL2 apoptosis regulator , Bcl-2 , PPP1R50

Cellular Localization

Mitochondrion outer membrane , Endoplasmic reticulum membrane

Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-Bcl-2 antibody [bcl-2/100/D5] used in IHC (Paraffin sections) (IHC-P). GTX01935

GTX01935 IHC-P Image

IHC-P analysis of human follicular lymphoma using GTX01935 Bcl-2 antibody [bcl-2/100/D5]. Neoplastic cells show a moderate, predominantly cytoplasmic staining reaction.

REFERENCE

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REVIEW

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Package List Price ($)
$ 409