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Bcl-XL antibody [4A9]

Overexpression
Anti-Bcl-XL antibody [4A9] used in Western Blot (WB). GTX84834
Anti-Bcl-XL antibody [4A9] used in IHC (Paraffin sections) (IHC-P). GTX84834
Anti-Bcl-XL antibody [4A9] used in IHC (Paraffin sections) (IHC-P). GTX84834
Anti-Bcl-XL antibody [4A9] used in Western Blot (WB). GTX84834
Anti-Bcl-XL antibody [4A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84834
Anti-Bcl-XL antibody [4A9] used in Western Blot (WB). GTX84834
Anti-Bcl-XL antibody [4A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84834

Cat. No. GTX84834

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4A9

Isotype

 IgG2a

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($519)
See all Bcl-XL products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200-1:1000
ICC/IF 1:100
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_10728062

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL2 like 1 , BCL-XL/S , BCL2L , BCLX , Bcl-X , PPP1R52

Cellular Localization

Mitochondrion outer membrane,Mitochondrion matrix,Cytoplasm, cytosol

Background

Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Isoform Bcl-X(S) promotes apoptosis.

Database

Research Area

DATA IMAGES

Anti-Bcl-XL antibody [4A9] used in Western Blot (WB). GTX84834

GTX84834 WB Image

WB analysis of various samples using GTX84834 Bcl-XL antibody [4A9].
Loading : 10 ug per lane
Dilution : 1:200

Anti-Bcl-XL antibody [4A9] used in IHC (Paraffin sections) (IHC-P). GTX84834

GTX84834 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX84834 Bcl-XL antibody [4A9].

Anti-Bcl-XL antibody [4A9] used in IHC (Paraffin sections) (IHC-P). GTX84834

GTX84834 IHC-P Image

IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84834 Bcl-XL antibody [4A9].

Anti-Bcl-XL antibody [4A9] used in Western Blot (WB). GTX84834

GTX84834 WB Image

WB analysis of various cell lines using GTX84834 Bcl-XL antibody [4A9].
Loading : 10 ug per lane
Dilution : 1:200

Anti-Bcl-XL antibody [4A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84834

GTX84834 ICC/IF Image

ICC/IF analysis of HT29 cells using GTX84834 Bcl-XL antibody [4A9].

Anti-Bcl-XL antibody [4A9] used in Western Blot (WB). GTX84834

GTX84834 WB Image

Overexpression

WB analysis of HEK293T cells transfected with Bcl-XL plasmid (Right) or empty vector (Left) for 48 hrs using GTX84834 Bcl-XL antibody [4A9].
Loading : 5 ug per lane

Anti-Bcl-XL antibody [4A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84834

GTX84834 ICC/IF Image

ICC/IF analysis of COS7 cells transiently transfected with Bcl-XL plasmid using GTX84834 Bcl-XL antibody [4A9].

REFERENCE

Application Reference

Ide T et al. Vet Pathol 2010; 47 (4) : 741-50 Immunohistochemical characterization of canine neuroepithelial tumors.
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519