GeneTex
United States (US)

Bcl rambo antibody [Rocky-2]

Cat No. GTX16096

Host Mouse
Clonality Monoclonal
Clone Name Rocky-2
Isotype IgG1
Application WB, ICC/IF, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1,000
ICC/IF 1:300
IP 1:100
Not tested in other applications.

Calculated MW

53 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment, corresponding to C terminal amino acids 224 - 459 of Human Bcl rambo, fused at the N terminus to a tag.

Purification

Purified IgG1
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Bcl2 Like 13,Bcl-Rambo,Bcl2-L-13,Mil1,Bcl2L13

Cellular Localization

Mitochondrial (isoform 2) and Nuclear (isoform 2 and 3)

Background

Bcl rambo shares common structural characteristics with other members of the anti-apoptotic Bcl2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence preceeds the membrane anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that its membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs. Bcl rambo may promote the activation of caspase-3 and apoptosis.

Database

Research Area

Package List Price ($)
$ 329